Portfolio

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Table of Contents

    White papers and ebooks

    This ebook successfully generated quality leads for ChemoMetec. My role was to lead the entire campaign, which included writing the content, leading the visual layout, and publicizing it across digital channels. I worked closely with the marketing team to segment customers for a LinkedIn campaign. Available here.

    This white paper targeted the academic research segment and was written in a different style than the previous. My role was to edit the ebook for clarity and accuracy and prepare copy for publication across all channels. Available here.

    SEO blogs

    I can get search engine optimized-articles to rank in the top 3 search positions on Google quickly. Maintaining this ranking requires continuous monitoring (rank tracking). My services help you devise a SEO content strategy and execute.

    Example 1: Advantages and disadvantages of the automated cell counter

    Example 2: How do automated cell counters work?

    Social Media (LinkedIn) posts

    Note: In addition to writing copy, I advise graphic designers on accompanying visuals. For simpler content, I create graphics myself using Canva. All excerpts from posts below are italicized and do not show other media.

    Example 1: A post about a small molecule CDMO’s services

    It takes 10 years and over $1 billion to develop a single drug.

    Quality issues in unsuccessful IND submissions delay drug development by up to 2 years. The most common causes? CMC problems and sponsors with limited regulatory experience.

    Our Dossier Development services provide full regulatory support prior to submission, during review, and post-approval to help you achieve your first clinical trial application. We offer CMC/RA support, nitrosamine and mutagenicity risk assessments, and regulatory starting material justification using a dossier-centric approach. 

    Find out more:

    #regulatorycompliance #cmc #drugdiscovery #cdmo #regulatoryaffairs

    Example 2: Analytical instrument company

    This post is an example of the benefits of capitalizing on recent news and posting something relevant right away.

    See how the NucleoCounter® was used in this manufacturing protocol for AMTAGVI (lifileucel), a TIL therapy that was recently granted accelerated approval for metastatic or unresectable melanoma.

    In this poster, Iovance Biotherapeutics, Inc. tested the reproducibility of the manufacturing process for lifileucel in other solid tumors, including:

    · Cervical cancer
    · Head and neck squamous cell carcinoma
    · Soft tissue sarcoma
    · Non-small cell lung cancer

    Their protocol was able to meet the minimal specification criteria of at least 70% cell viability and at least 1 billion total viable cells—both of which are measured on the NucleoCounter® for precise results.

    It will be exciting to see how TIL therapy manufacturing develops! Follow us for more information like this and get in touch to learn more about our NucleoCounter® technology.

    Example 3: Post about mesenchymal stem cells that generated more engagement than usual

    This LinkedIn post summarized a relevant publication, tagged authors, and included an uploaded pdf for better engagement.

    The freezer-to-vein workflow challenge in cell therapy

    Manufacturing mesenchymal stem cell (MSC)-based therapies is a challenge unto itself. But this is only half the battle.

    Cells taken out of the cryo-freezer are fragile. To maintain potency before the therapy is administered to patients, the cells must be handled carefully.

    Another challenge is bringing these medicines to critical patients in time. The best way to achieve this is through allogeneic (off-the-shelf) approaches. Currently, there are no best practices for the freezer-to-vein workflow for allogeneic MSC-based therapies.

    A team of dedicated researchers at the Center for Gene and Cellular Therapy, Aarhus University Hospital, is committed to streamlining MSC handling from the moment of thawing to the point of administration to enhance patient care.

    Driven by this goal, first authors Dr. Rasmus Aabling and Dr. Toke Alstrup from Aarhus Universitetshospital have shared their latest findings in a recently published work.

    The Danish team of researchers conducted a series of experiments to determine:

    ● the optimal cell concentration for reconstitution
    ● the most suitable medium for reconstitution
    ● the impact of protein-free solutions on cell viability

    Through their exploration of these critical knowledge gaps, they have advanced the standardization of MSC-handling protocols before cell therapy administration. The study employed the NucleoCounter® NC-202™ and flow cytometer-based characterization of the cellular products to ensure precision and accuracy in their assessments.

    Congratulations to the authors on these research achievements!

    To delve deeper into their findings, we invite you to read the complete paper below.

    Example 3: Post on my own feed about gene therapy

    John was completely blind. 𝗡𝗼𝘄 𝗵𝗲 𝗰𝗮𝗻 𝗽𝗹𝗮𝘆 𝗴𝗼𝗹𝗳 𝗮𝗻𝗱 𝘄𝗮𝘁𝗰𝗵 𝗵𝗶𝘀 𝗴𝗿𝗮𝗻𝗱𝗸𝗶𝗱𝘀 𝗴𝗿𝗼𝘄 𝘂𝗽 𝘁𝗵𝗮𝗻𝗸𝘀 𝘁𝗼 𝗼𝗽𝘁𝗼𝗴𝗲𝗻𝗲𝘁𝗶𝗰 𝗴𝗲𝗻𝗲 𝘁𝗵𝗲𝗿𝗮𝗽𝘆.

    👁️ Optogenetic gene therapy involves bringing light-sensitizing capabilities back to cells in the eye, where photoreceptors have degenerated. A company to watch, Nanoscope Therapeutics Inc., is developing the only gene therapy based on opsins, proteins that help us see, to tackle both 𝘳𝘦𝘵𝘪𝘯𝘪𝘵𝘪𝘴 𝘱𝘪𝘨𝘮𝘦𝘯𝘵𝘰𝘴𝘢 and 𝘚𝘵𝘢𝘳𝘨𝘢𝘳𝘥𝘵 𝘥𝘪𝘴𝘦𝘢𝘴𝘦.

    🧬 The therapy, MCO-010, doesn’t rely on viral vectors, and patients describe the intravitreal injection as completely painless. I liked Joe’s story so much I made some edits of the video, sourced from Nanoscope’s website.

    📊 In March, the company reported top line results from the RESTORE phase 2b trial, which achieved its primary endpoint and is expected to submit a BLA later this year. For more clinical trial info read the press release: https://lnkd.in/dNxg3v97

    As a side note, Nanoscope Therapeutics is a spin-off from Nanoscope Technologies, which also developed the non-viral in vivo gene delivery method used for this gene therapy. Link to the paper on that in the comments.

    Publications